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The

Nano-Safety Research Group

Specialists in the assessment of nanomaterial toxicity to human health and the environment

Corin Liddle

Corin profileNanotechnology is involved in the production of many mainstream consumer products, as well as industrial processes and medicine. Given the widespread use of nanomaterials in so many applications their release (whether accidental or intentional) into the environment is inevitable. At this point it is still unclear where these nanomaterials will end up in the environment and how much of a threat they may pose.

Corin's research aims to investigate the conditions that affect silver (Ag) nanomaterial (NM) toxicity in lentic (static) and lotic (flowing) freshwater environments, and identify what environmental conditions may lead to higher hazard, using Zebrafish, Danio rerio and Californian Black worm, Lumbriculus variegatus as model organisms. The approach is to investigate how environmentally relevant water chemistry, sediments and turbulence affects the toxicity of Ag NMs, using a range of endpoints: mortality, deformities, behaviour and specific biomarkers e.g. metallothionein gene expression (MT2) and metallothionein like proteins (MTLP). In parallel, the fate and behaviour of Ag NM will be investigated via the characterisation of NM physico-chemical properties, such as: agglomeration/aggregation state, dissolution and NM surface modifications, where possible.

Supervisors

Prof Teresa Fernandes (School of Life Sciences, Heriot-Watt Universty)

Dr Heather Haynes (School of the Built Environment, Heriot-Watt Universty)

Dr Alan Cuthbertson (School of the Built Environment, Heriot-Watt Universty)

Funding 

Heriot-Watt University James Watt Studentship

Email Corin: ccl32@hw.ac.uk