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The

Nano-Safety Research Group

Specialists in the assessment of nanomaterial toxicity to human health and the environment

Daniele Pantano

daniele pictureSUN (Sustainable Nanotechnologies) is the first project addressing the entire lifecycle of nanotechnologies to ensure holistic nanosafety evaluation and incorporate the results into tools and guidelines for sustainable manufacturing, easily accessible by industries, regulators and other stakeholders.

The project incorporates scientific findings from over 30 European projects, national and international research programmes and transatlantic co-operations to develop (i) methods and tools to predict nanomaterials exposure and effects on humans and ecosystems, (ii) implementable processes to reduce hazard and exposure to nanomaterials in different lifecycle stages, (iii) innovative technological solutions for risk management in industrial settings, and (iv) guidance on best practices for securing both nano-manufacturing processes and nanomaterials ultimate fate, including development of approaches for safe disposal and recycling.

Specifically our team will investigate the hazards of pristine and released/aged nanoparticles using in vitro screens combined with in vivo models for important routes of exposure to generate hazard data suitable for human hazard identification and risk assessment.

Thus, I will use C3A hepatocyte and dermal (EpiDermFTTM) cell lines to screen the acute (24h) cytotoxicity (Alamar Blue, WST-1 or LDH), inflammatory (Luminex, Multiplex or FACS array) and genotoxicity (Comet assay) of SUN priority nanoparticles.

Supervisors

  • Prof.  Vicki Stone (School of Life Sciences, Heriot-Watt University)
  • Dr. Helinor Johnston (School of Life Sciences, Heriot-Watt University)

Funding

Framework Programme 7 (FP7): SUN (Sustainable Nanotechnologies) project

Project Website: http://www.sun-fp7.eu/

        

Email Daniele: dp163@hw.ac.uk