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The

Nano-Safety Research Group

Specialists in the assessment of nanomaterial toxicity to human health and the environment

Hassien Alnashiri

HassienCopper oxide nanomaterials (CuO NMs) are one type of nanomaterials that are widely used in various industrial and commercial applications, such as batteries, inks and heat transfer nanofluids. Thus, this widespread use will most likely lead to a potential increase in the release of CuO NMs into the environment, particularly the marine environment since it is an ultimate sink for contaminants. However, the knowledge of the toxicity of CuO NMs is still limited compared to other metal oxides such as zinc oxide (ZnO) or titanium dioxide (TiO2).

Hence, it is essential to investigate CuO NM exposure, uptake and effects on key organisms, such as benthic filter feeders since data in these systems and on these species are still lacking. So far, very few studies have determined the effect of CuO NMs on mussels, and these have concentrated solely on oxidative stress and lipid peroxidation. No study has previously investigated the toxicity of the CuO NMs on DNA damage and cell viability.
 
Thus, Hassien's study is determining and comparing the toxicity of CuO NMs (between 1- 100 nm) to two species of mussels (Mytilus edulis and Modiolus modiolus) by using multiple biomarkers. Using multiple approaches he is assessing DNA damage and cell viability, including a comet assay for determining DNA damage and flow cytometry for measuring cell viability.
 
Supervisors
Prof. Teresa Fernandes (School of Life Sciences, Heriot-Watt University)
Dr. Mark Hartl (School of Life Sciences, Heriot-Watt University)
 
Funding
The Royal Embassy of Saudi Arabia and Jazan University
Jazan University Saudi Arabia Ministry of High Education Saudi Arabia 1
 
Email Hassien: hmha1@hw.ac.uk